2. John Wilkes, Sr (Francis1) was born about 1736 in , , Pennsylvania, USA and died after 1795.
John married Elizabeth Mead in Apr 1758 in , Loudoun, Virginia, USA, daughter of Samuel Mead and Mary Downey. Elizabeth was born about 1740 in , , Pennsylvania Or Virginia, USA.
Children from this marriage were:
+ 4 M i. Henry Wilkes was born about 1758 and died in 1794 about age 36.
+ 5 M ii. Francis Wilkes was born about 1760 in , Loudoun, Virginia, USA and died after 1840 in , Lawrence, Ohio, USA.
+ 6 M iii. Benjamin Wilkes was born in 1762 in , Loudoun, Virginia, USA and died in 1809 in , Oglethorpe, Georgia, USA at age 47.
+ 7 M iv. Samuel Wilkes was born on 24 Oct 1764 in , Loudoun, Virginia, USA and died on 1 Jul 1837 in , Bedford, Virginia, USA at age 72.
+ 8 F v. Ann Wilkes was born in 1768 in , , Virginia, USA.
+ 9 F vi. Sally Wilkes was born in 1774 in , Bedford, Virginia, USA and died in , Patrick, Virginia, USA.
+ 10 M vii. John Wilkes, Jr was born in 1775 in , Bedford, Virginia, USA and died in 1836 in , Yallabusha, Mississippi, USA at age 61.
+ 11 M viii. Amos Wilkes was born in 1777 in , , Virginia, USA and died in 1850 in , Lawrence, Missouri, USA at age 73.
+ 12 M ix. Jesse J Wilkes was born in 1779 in , , Virginia, USA and died in 1830 in , Lauderdale, Alabama, USA at age 51.
+ 13 F x. Rachel Wilkes .
3. Samuel Wilkes (Francis1) died in 1813 in , Culpeper, Virginia, USA.
Samuel married Rebecca Unknown.